Why Eye Care Professionals Trust Zocular

 

Clinical Evidence Hub

Research, trials, and expert coverage

A single place to review published research, registered studies, and independent coverage related to Zocular and ZEST. This page is intended for education and reference.

  • Peer-reviewed publication
  • Registered clinical trial
  • Independent media + expert videos
  • Primary sources linked

Peer-reviewed

Published clinical study

International Journal of Ophthalmology • July 18, 2023 • PMCID: PMC10333254

Lid scrubbing with a gel combining natural extracts for dry eye treatment — retrospective evaluation measuring tear film stability, corneal staining, OSDI, and ocular pain before and after an in-clinic lid scrubbing procedure.

Clinical trials

Registered interventional study

ClinicalTrials.gov • NCT03968731 • 2019–2020 (Completed)

ZEST for Meibomian Gland Dysfunction & Contact Lens Intolerance — registered trial evaluating outcomes related to MGD symptoms and contact lens comfort in patients with blepharitis and daily contact lens wear.

Uptown Eye Specialists • August 14, 2023 • NCT05990712

The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers — registered study assessing two pre-operative ocular hygiene regimens prior to cataract surgery, both using at-home lid wipes and cleansing drops, with one arm including omega-3 supplementation.

Clinical context

Lid hygiene, Demodex, and okra-related evidence

PubMed Central • 2021 • PMCID: PMC7903416

Anti-demodectic effects of an okra eyelid patch in Demodex blepharitis — prospective comparison evaluating Demodex counts, OSDI symptoms, TBUT, corneal staining, and meibomian gland measures (meibum quality, expressibility) over 3 months.

Review article • 2023 • PMCID: PMC10788755

Eyelid cleaning: methods, evidence, and role in blepharitis management — clinical overview of lid hygiene approaches and their importance in ocular surface disease and evaporative dry eye care.

Note: Ingredient-focused studies provide background context. Outcomes vary by formulation, patient population, and underlying lid margin disease.

Independent coverage

Press, professional features, and distribution

Professional + industry coverage
Optometry Today (AOP) • May 27, 2025

“Setting Up a Dry Eye Clinic” — ZEST showcased at 100% Optical

Huddersfield Hub • October 20, 2025

“The Body Doctor Brings New Treatment for Dry Eye Disease to Boots Opticians”

Consumer / beauty press
Who What Wear • February 6, 2025

“An Ophthalmologist Taught Me How to Restore Lash Loss — Now, Mine Are the Healthiest They’ve Ever Been”

Distribution / corporate
NovaBay Pharmaceuticals press release • August 19, 2021

NovaBay Pharmaceuticals to Distribute Zocular® Dry Eye Products

Podcast mention
LuAnna: The Podcast • November 17, 2025

“I honestly have no words for this one.” — episode referenced on the Zocular Press & Media page.

Expert videos

Independent YouTube coverage + clinician education

David Keith YouTube • April 10, 2025

Dr. Peter Pham Answers Top Questions About Zocular Dry Eye Solutions

Dr. EyeGuy YouTube • 2025

I Found the BEST Eyelid Wipes for Blepharitis and Dry Eyes (2025)

Dry Eye Tips YouTube • August 26, 2024

Unlocking Okra's Secrets: How It Can Soothe Your Eyes and Ease Pain!

Dr. Brandon Walley YouTube • May 20, 2023

ZocuFoam Eyelid Cleanser For Dry Eyes — Review

Source of truth

Master list (Press & Media)

This hub curates the evidence links currently listed on your Press & Media page. Keep that page updated and this hub stays accurate.